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Reading: Pfizer Charts New Path to Growth Amid Vaccine Decline and Patent Expirations
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Pfizer Charts New Path to Growth Amid Vaccine Decline and Patent Expirations

News Desk
Last updated: February 20, 2026 9:38 am
News Desk
Published: February 20, 2026
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Pfizer is undergoing a significant transformation as it navigates the changing landscape of the pharmaceutical industry. Once hailed for its blockbuster coronavirus vaccine, which generated over $37 billion at its peak in 2022 and propelled the company to annual revenues exceeding $100 billion, Pfizer faces a new reality. With demand for the vaccine waning and the impending loss of exclusivity for several of its older, high-revenue drugs, the company is strategizing effectively to adapt and grow.

The loss of patent protection for key products like the blood thinner Eliquis and the breast cancer treatment Ibrance signals an end to an era of major revenue from these offerings. Recognizing potential declines in these sources of income, Pfizer has taken proactive steps. The company has realigned its financial strategies to reflect reduced coronavirus vaccine profits while intensifying focus on in-house research and development alongside strategic acquisitions.

One of the notable acquisitions is Pfizer’s purchase of Seagen, which has introduced several commercially successful drugs into its portfolio. Among these is Padcev, a treatment for bladder cancer, which has achieved blockbuster status with over $1 billion in annual revenue and has been demonstrating double-digit growth. This acquisition underscores Pfizer’s commitment to expanding its oncology footprint.

Additionally, Pfizer is making inroads into the lucrative weight loss drug market. Recently acquiring Metsera, a company focused on developing weight loss therapies, Pfizer aims to capitalize on a sector projected to approach $100 billion by the end of the decade. Analysts note that the weight loss market currently dominated by Eli Lilly and Novo Nordisk has room for multiple competitors, and Pfizer’s research is already exploring innovative approaches, such as a potential monthly dosing regimen for its Metsera candidate, which could differentiate it from existing weekly-dosing options. Moreover, the company is advancing 10 obesity studies currently in phase 3, suggesting that a commercial launch might be on the horizon.

Amid this transition, Pfizer has reported impressive growth in revenue from recent product launches and acquisitions, with total earnings surpassing $10 billion last year, a notable increase from $8.9 billion the previous year. The firm is on track to achieve its cost-savings targets and plans to reinvest $500 million into research and development by year-end.

With these strategies in place, Pfizer appears well positioned for a future of sustainable growth, suggesting it may offer resilience and stability in challenging market conditions. Investors may view Pfizer as a strong candidate for long-term holding, particularly in the face of any potential market downturns.

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